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Suppression of human DNA alkylation-repair defects by Escherichia coli DNA-repair genes.

The ada-alkB operon protects Escherichia coli against the effects of many alkylating agents. We have subcloned it into the pSV2 mammalian expression vector to yield pSV2ada-alkB, and this plasmid has been introduced into Mer- HeLa S3 cells, which are extremely sensitive to killing and induction of s...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Samson, L, Derfler, B, Waldstein, E A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386337/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3526337/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.15.5607
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