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miR-219 Regulates Neural Precursor Differentiation by Direct Inhibition of Apical Par Polarity Proteins

Asymmetric self-renewing division of neural precursors is essential for brain development. Partition defective (Par) proteins promote self-renewal, and their asymmetric distribution provides a mechanism for asymmetric division. Near the end of neural development, most asymmetric division ends and pr...

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Detalhes bibliográficos
Main Authors: Hudish, Laura I., Blasky, Alex J., Appel, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862977/
https://ncbi.nlm.nih.gov/pubmed/24239515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.10.015
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