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miR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signaling
The transition of dividing neuroepithelial progenitors to differentiated neurons and glia is essential for the formation of a functional nervous system. Sonic hedgehog (Shh) is a mitogen for spinal cord progenitors, but how cells become insensitive to the proliferative effects of Shh is not well und...
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| Pubblicato in: | Development |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4958328/ https://ncbi.nlm.nih.gov/pubmed/27226318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.137844 |
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