ADP Protects Cardiac Mitochondria under Severe Oxidative Stress

ADP is not only a key substrate for ATP generation, but also a potent inhibitor of mitochondrial permeability transition pore (mPTP). In this study, we assessed how oxidative stress affects the potency of ADP as an mPTP inhibitor and whether its reduction of reactive oxygen species (ROS) production...

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Detalhes bibliográficos
Main Authors: Sokolova, Niina, Pan, Shi, Provazza, Sarah, Beutner, Gisela, Vendelin, Marko, Birkedal, Rikke, Sheu, Shey-Shing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862761/
https://ncbi.nlm.nih.gov/pubmed/24349464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083214
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