ADP Compartmentation Analysis Reveals Coupling between Pyruvate Kinase and ATPases in Heart Muscle

Cardiomyocytes have intracellular diffusion restrictions, which spatially compartmentalize ADP and ATP. However, the models that predict diffusion restrictions have used data sets generated in rat heart permeabilized fibers, where diffusion distances may be heterogeneous. This is avoided by using is...

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Detalhes bibliográficos
Main Authors: Sepp, Mervi, Vendelin, Marko, Vija, Heiki, Birkedal, Rikke
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Biological Systems and Multicellular Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884246/
https://ncbi.nlm.nih.gov/pubmed/20550890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.025
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