ADP Compartmentation Analysis Reveals Coupling between Pyruvate Kinase and ATPases in Heart Muscle

Cardiomyocytes have intracellular diffusion restrictions, which spatially compartmentalize ADP and ATP. However, the models that predict diffusion restrictions have used data sets generated in rat heart permeabilized fibers, where diffusion distances may be heterogeneous. This is avoided by using is...

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Bibliographic Details
Main Authors: Sepp, Mervi, Vendelin, Marko, Vija, Heiki, Birkedal, Rikke
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Biological Systems and Multicellular Dynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884246/
https://ncbi.nlm.nih.gov/pubmed/20550890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.025
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