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Marker enzyme activities in hindleg from creatine-deficient AGAT and GAMT KO mice – differences between models, muscles, and sexes

Creatine kinase (CK) functions as an energy buffer in muscles. Its substrate, creatine, is generated by L-arginine:glycine amidinotransferase (AGAT) and guanidinoacetate N-methyltransferase (GAMT). Creatine deficiency has more severe consequences for AGAT than GAMT KO mice. In the present study, to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Barsunova, Karina, Vendelin, Marko, Birkedal, Rikke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224371/
https://ncbi.nlm.nih.gov/pubmed/32409787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64740-8
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