Identification of ciliary neurotrophic factor (CNTF) residues essential for leukemia inhibitory factor receptor binding and generation of CNTF receptor antagonists.
Ciliary neurotrophic factor (CNTF) drives the sequential assembly of a receptor complex containing the ligand-specific alpha-receptor subunit (CNTFR alpha) and the signal transducers gp130 and leukemia inhibitory factor receptor-beta (LIFR). The D1 structural motif, located at the beginning of the D...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1996
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38627/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799186/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.9247 |
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