Identification of mutations in TgMAPK1 of Toxoplasma gondii conferring resistance to 1NM-PP1()

Toxoplasma gondii is an important food and waterborne pathogen that causes severe disease in immunocompromised patients. Bumped kinase inhibitors (BKIs) have an antiparasitic effect on T. gondii tachyzoite growth by targeting T. gondii calmodulin-domain protein kinase 1 (TgCDPK1). To identify mutati...

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Autors principals: Sugi, Tatsuki, Kobayashi, Kyousuke, Takemae, Hitoshi, Gong, Haiyan, Ishiwa, Akiko, Murakoshi, Fumi, Recuenco, Frances C., Iwanaga, Tatsuya, Horimoto, Taisuke, Akashi, Hiroomi, Kato, Kentaro
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862444/
https://ncbi.nlm.nih.gov/pubmed/24533298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2013.04.001
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