Identification of mutations in TgMAPK1 of Toxoplasma gondii conferring resistance to 1NM-PP1()

Toxoplasma gondii is an important food and waterborne pathogen that causes severe disease in immunocompromised patients. Bumped kinase inhibitors (BKIs) have an antiparasitic effect on T. gondii tachyzoite growth by targeting T. gondii calmodulin-domain protein kinase 1 (TgCDPK1). To identify mutati...

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Detalhes bibliográficos
Main Authors: Sugi, Tatsuki, Kobayashi, Kyousuke, Takemae, Hitoshi, Gong, Haiyan, Ishiwa, Akiko, Murakoshi, Fumi, Recuenco, Frances C., Iwanaga, Tatsuya, Horimoto, Taisuke, Akashi, Hiroomi, Kato, Kentaro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862444/
https://ncbi.nlm.nih.gov/pubmed/24533298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2013.04.001
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