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Exposing the Specific Roles of the Invariant Chain Isoforms in Shaping the MHC Class II Peptidome
The peptide repertoire (peptidome) associated with MHC class II molecules (MHCIIs) is influenced by the polymorphic nature of the peptide binding groove but also by cell-intrinsic factors. The invariant chain (Ii) chaperones MHCIIs, affecting their folding and trafficking. Recent discoveries relatin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3861868/ https://ncbi.nlm.nih.gov/pubmed/24379812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00443 |
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