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Exposing the Specific Roles of the Invariant Chain Isoforms in Shaping the MHC Class II Peptidome

The peptide repertoire (peptidome) associated with MHC class II molecules (MHCIIs) is influenced by the polymorphic nature of the peptide binding groove but also by cell-intrinsic factors. The invariant chain (Ii) chaperones MHCIIs, affecting their folding and trafficking. Recent discoveries relatin...

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Bibliografski detalji
Glavni autori: Fortin, Jean-Simon, Cloutier, Maryse, Thibodeau, Jacques
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861868/
https://ncbi.nlm.nih.gov/pubmed/24379812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00443
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