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Glycolytic ATP Fuels the Plasma Membrane Calcium Pump Critical for Pancreatic Cancer Cell Survival

Pancreatic cancer is an aggressive cancer with poor prognosis and limited treatment options. Cancer cells rapidly proliferate and are resistant to cell death due, in part, to a shift from mitochondrial metabolism to glycolysis. We hypothesized that this shift is important in regulating cytosolic Ca(...

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Sonraí Bibleagrafaíochta
Main Authors: James, Andrew D., Chan, Anthony, Erice, Oihane, Siriwardena, Ajith K., Bruce, Jason I. E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861649/
https://ncbi.nlm.nih.gov/pubmed/24158437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.502948
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