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Identification of Putative Target Genes of the Transcription Factor RUNX2

Comparisons of the genomes of Neandertals and Denisovans with present-day human genomes have suggested that the gene RUNX2, which encodes a transcription factor, may have been positively selected during early human evolution. Here, we overexpress RUNX2 in ten human cell lines and identify genes that...

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Detalles Bibliográficos
Main Authors: Kuhlwilm, Martin, Davierwala, Armaity, Pääbo, Svante
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861491/
https://ncbi.nlm.nih.gov/pubmed/24349465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083218
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