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Molecular Basis of Drug Resistance: Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Anaplastic Lymphoma Kinase Inhibitors

Over the past decade, several kinase inhibitors have been approved based on their clinical benefit in cancer patients. Unfortunately, in many cases, patients develop resistance to these agents via secondary mutations and alternative mechanisms. To date, several major mechanisms of acquired resistanc...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
מחבר ראשי: Yang, Sei-Hoon
פורמט: Artigo
שפה:Inglês
יצא לאור: The Korean Academy of Tuberculosis and Respiratory Diseases 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861374/
https://ncbi.nlm.nih.gov/pubmed/24348666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4046/trd.2013.75.5.188
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