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Resistance to epidermal growth factor receptor tyrosine kinase inhibitors, T790M, and clinical trials

Tumours with sensitizing mutations in the EGFR gene constitute a distinct molecular subgroup of non-small-cell lung cancers (nsclcs) that benefit from precision medicine. First- and second-generation epidermal growth factor receptor (egfr) tyrosine kinase inhibitors (tkis) are recommended as upfront...

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Detalhes bibliográficos
Publicado no:Curr Oncol
Main Authors: O’Kane, G.M., Barnes, T.A., Leighl, N.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Multimed Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001758/
https://ncbi.nlm.nih.gov/pubmed/29910645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3747/co.25.3796
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