An Lmx1b-miR135a2 Regulatory Circuit Modulates Wnt1/Wnt Signaling and Determines the Size of the Midbrain Dopaminergic Progenitor Pool

MicroRNAs regulate gene expression in diverse physiological scenarios. Their role in the control of morphogen related signaling pathways has been less studied, particularly in the context of embryonic Central Nervous System (CNS) development. Here, we uncover a role for microRNAs in limiting the spa...

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Main Authors: Anderegg, Angela, Lin, Hsin-Pin, Chen, Jun-An, Caronia-Brown, Giuliana, Cherepanova, Natalya, Yun, Beth, Joksimovic, Milan, Rock, Jason, Harfe, Brian D., Johnson, Randy, Awatramani, Rajeshwar
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861205/
https://ncbi.nlm.nih.gov/pubmed/24348261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003973
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