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TLR2 Ligands Induce NF-κB Activation from Endosomal Compartments of Human Monocytes
Localization of Toll-like receptors (TLR) in subcellular organelles is a major strategy to regulate innate immune responses. While TLR4, a cell-surface receptor, signals from both the plasma membrane and endosomal compartments, less is known about the functional role of endosomal trafficking upon TL...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3861177/ https://ncbi.nlm.nih.gov/pubmed/24349012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080743 |
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