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SOCS1 regulates the IFN but not NFκB pathway in TLR-stimulated human monocytes and macrophages
SOCS1 can regulate TLR-mediated signal transduction, yet mechanistic studies in murine macrophages have been confusing and contradictory. This study has used an adenoviral transfection system to determine the role of SOCS1 in the regulation of TNFα production by activated human monocytes. Monocytes...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430718/ https://ncbi.nlm.nih.gov/pubmed/19017994 |
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