Suppressor of cytokine signalling-3 at pathological levels does not regulate lipopolysaccharide or interleukin-10 control of tumour necrosis factor-α production by human monocytes

Interleukin-10 (IL-10) is a potent anti-inflammatory cytokine that suppresses the production of tumour necrosis factor-α (TNF-α) by monocytes and macrophages. Suppressor of cytokine signalling-3 (SOCS3), a negative regulator of the Janus kinase (JAK)/signal transducer and activator of transcription...

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Detalhes bibliográficos
Main Authors: Prêle, Cecilia M, Keith-Magee, April L, Yerkovich, Stephanie T, Murcha, Monika, Hart, Prue H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782329/
https://ncbi.nlm.nih.gov/pubmed/16925527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02383.x
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