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Post-GWAS: where next? More samples, more SNPs or more biology?
The power of genome-wide association studies (GWAS) rests on several foundations: (i) there is a significant amount of additive genetic variation, (ii) individual causal polymorphisms often have sizable effects and (iii) they segregate at moderate-to-intermediate frequencies, or will be effectively...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3860164/ https://ncbi.nlm.nih.gov/pubmed/23759726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2013.52 |
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