MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma

Our laboratory recently reported that treatment with the d-amino acid containing peptide HYD1 induces necrotic cell death in multiple myeloma (MM) cell lines. Due to the intriguing biological activity and promising in vivo activity of HYD1, we pursued strategies for increasing the therapeutic effica...

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Hlavní autoři: Gebhard, Anthony W., Jain, Priyesh, Nair, Rajesh R., Emmons, Michael F., Argilagos, Raul F., Koomen, John M., McLaughlin, Mark L., Hazlehurst, Lori A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859963/
https://ncbi.nlm.nih.gov/pubmed/24048737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0310
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