Epigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer

BACKGROUND: We evaluated the clinical prognostic value of methylation of two non-coding repeat sequences, long interspersed element 1 (LINE-1) and Alu, in rectal tumour tissues. In addition to DNA methylation, expression of histone modifications H3K27me3 and H3K9Ac was studied in this patient cohort...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Benard, A, van de Velde, C J H, Lessard, L, Putter, H, Takeshima, L, Kuppen, P J K, Hoon, D S B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859941/
https://ncbi.nlm.nih.gov/pubmed/24220694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.654
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars