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Targeting concatenated HIV antigens to human CD40 expands a broad repertoire of multifunctional CD4(+) and CD8(+) T cells

OBJECTIVE: Targeting HIV antigens directly to dendritic cells using monoclonal antibodies against cell-surface receptors has been shown to evoke potent cellular immunity in animal models. The objective of this study was to configure an anti-human CD40 antibody fused to a string of five highly conser...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Flamar, Anne-Laure, Xue, Yaming, Zurawski, Sandra M., Montes, Monica, King, Bryan, Sloan, Louis, Oh, SangKon, Banchereau, Jacques, Levy, Yves, Zurawski, Gerard
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859846/
https://ncbi.nlm.nih.gov/pubmed/23615121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3283624305
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