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Antimicrobial efflux pumps and Mycobacterium tuberculosis drug tolerance: Evolutionary Considerations
The need for lengthy treatment to cure tuberculosis stems from phenotypic drug resistance, also known as drug tolerance, which has been previously attributed to slowed bacterial growth in vivo. We discuss recent findings that challenge this model and instead implicate macrophage-induced mycobacteria...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3859842/ https://ncbi.nlm.nih.gov/pubmed/23242857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2012_300 |
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