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Central cholinergic activation of a vagus nerve - to spleen circuit alleviates experimental colitis

The cholinergic anti-inflammatory pathway is an efferent vagus nerve-based mechanism that regulates immune responses and cytokine production through α7nicotinic-acetylcholinereceptor (α7nAChR) signaling. Decreased efferent vagus nerve activity is observed in inflammatory bowel disease (IBD). We dete...

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Detalhes bibliográficos
Main Authors: Ji, Hong, Rabbi, Mohammad F, Labis, Benoit, Pavlov, Valentin A, Tracey, Kevin J, Ghia, Jean-Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859808/
https://ncbi.nlm.nih.gov/pubmed/23881354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.52
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