Central Muscarinic Cholinergic Activation Alters Interaction between Splenic Dendritic Cell and CD4(+)CD25(-) T Cells in Experimental Colitis

BACKGROUND: The cholinergic anti-inflammatory pathway (CAP) is based on vagus nerve (VN) activity that regulates macrophage and dendritic cell responses in the spleen through alpha-7 nicotinic acetylcholine receptor (a7nAChR) signaling. Inflammatory bowel disease (IBD) patients present dysautonomia...

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Detalhes bibliográficos
Main Authors: Munyaka, Peris, Rabbi, Mohammad F., Pavlov, Valentin A., Tracey, Kevin J., Khafipour, Ehsan, Ghia, Jean-Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190311/
https://ncbi.nlm.nih.gov/pubmed/25295619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109272
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