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Central Muscarinic Cholinergic Activation Alters Interaction between Splenic Dendritic Cell and CD4(+)CD25(-) T Cells in Experimental Colitis
BACKGROUND: The cholinergic anti-inflammatory pathway (CAP) is based on vagus nerve (VN) activity that regulates macrophage and dendritic cell responses in the spleen through alpha-7 nicotinic acetylcholine receptor (a7nAChR) signaling. Inflammatory bowel disease (IBD) patients present dysautonomia...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4190311/ https://ncbi.nlm.nih.gov/pubmed/25295619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109272 |
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