TLR9 adjuvants enhance immunogenicity and protective efficacy of the SE36/AHG malaria vaccine in nonhuman primate models

The SE36 antigen, derived from serine repeat antigen 5 (SERA5) of Plasmodium falciparum, is a promising blood stage malaria vaccine candidate. Ongoing clinical trials suggest the efficacy of the SE36 vaccine could be increased by the incorporation of more effective adjuvants into the vaccine formula...

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Detalhes bibliográficos
Main Authors: Tougan, Takahiro, Aoshi, Taiki, Coban, Cevayir, Katakai, Yuko, Kai, Chieko, Yasutomi, Yasuhiro, Ishii, Ken J., Horii, Toshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859748/
https://ncbi.nlm.nih.gov/pubmed/23291928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.22950
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