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Sleep Modifies the Relation of APOE to the Risk of Alzheimer Disease and Neurofibrillary Tangle Pathology

IMPORTANCE: The Apolipoprotein E (APOE) ε4 allele is a common and well-established genetic risk factor for Alzheimer Disease (AD). Sleep consolidation is also associated with AD risk and previous work suggests that APOE genotype and sleep may interact to influence cognitive function. OBJECTIVE: To d...

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Detalhes bibliográficos
Main Authors: Lim, Andrew S.P., Yu, Lei, Kowgier, Matthew, Schneider, Julie A., Buchman, Aron S., Bennett, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859706/
https://ncbi.nlm.nih.gov/pubmed/24145819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.4215
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