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Nonsteroidal anti-inflammatory drug sulindac sulfide suppresses structural protein Nesprin-2 expression in colorectal cancer cells

BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) are well known for treating inflammatory disease and have been reported to have anti-tumorigenic effects. Their mechanisms are not fully understood, but both cyclooxygenase (COX) dependent and independent pathways are involved. Our goal was t...

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Main Authors: Liggett, Jason L., Choi, Chang K., Donnell, Robert L., Kihm, Kenneth D., Kim, Jong-Sik, Min, Kyung-Won, Noegel, Angelika Anna, Baek, Seung Joon
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859692/
https://ncbi.nlm.nih.gov/pubmed/24080406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.09.032
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