HDAC Inhibitors Repress BARD1 Isoform Expression in Acute Myeloid Leukemia Cells via Activation of miR-19a and/or b

Over the past years BARD1 (BRCA1-associated RING domain 1) has been considered as both a BRCA1 (BReast Cancer susceptibility gene 1, early onset) interactor and tumor suppressor gene mutated in breast and ovarian cancers. Despite its role as a stable heterodimer with BRCA1, increasing evidence indic...

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Main Authors: Lepore, Ilaria, Dell’Aversana, Carmela, Pilyugin, Maxim, Conte, Mariarosaria, Nebbioso, Angela, De Bellis, Floriana, Tambaro, Francesco P., Izzo, Tiziana, Garcia-Manero, Guillermo, Ferrara, Felicetto, Irminger-Finger, Irmgard, Altucci, Lucia
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859623/
https://ncbi.nlm.nih.gov/pubmed/24349422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083018
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