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Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy
One arising challenge in the treatment of breast cancer is development of therapeutic resistance to trastuzumab, an antibody targeting the human epidermal growth factor receptor-2 (HER2) which is frequently amplified in breast cancers. In this study, we provide evidence that elevated level of the re...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3859619/ https://ncbi.nlm.nih.gov/pubmed/20028874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1845 |
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