Fibroblast Growth Factor Receptor 1 Signaling in Adult Cardiomyocytes Increases Contractility and Results in a Hypertrophic Cardiomyopathy

Fibroblast growth factors (FGFs) and their receptors are highly conserved signaling molecules that have been implicated in postnatal cardiac remodeling. However, it is not known whether cardiomyocyte-expressed FGF receptors are necessary or sufficient for ventricular remodeling in the adult heart. T...

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Bibliographic Details
Main Authors: Cilvik, Sarah N., Wang, Joy I., Lavine, Kory J., Uchida, Keita, Castro, Angela, Gierasch, Carolyn M., Weinheimer, Carla J., House, Stacey L., Kovacs, Attila, Nichols, Colin G., Ornitz, David M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859602/
https://ncbi.nlm.nih.gov/pubmed/24349409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082979
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