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Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice

Hedgehog (HH) signaling has emerged as a critical pathway involved in the pathogenesis of a variety of tumors. As a result, HH antagonists are currently being evaluated as potential anticancer therapeutics. Conversely, activation of HH signaling in the adult heart may be beneficial, as HH agonists h...

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Bibliografiske detaljer
Main Authors: Lavine, Kory J., Kovacs, Attila, Ornitz, David M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430494/
https://ncbi.nlm.nih.gov/pubmed/18568073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34561
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