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Inhibiting CXCR3-Dependent CD8(+) T Cell Trafficking Enhances Tolerance Induction in a Mouse Model of Lung Rejection

Lung transplantation remains the only effective therapy for patients with end-stage pulmonary diseases. Unfortunately, acute rejection of the lung remains a frequent complication and is an important cause of morbidity and mortality. The induction of transplant tolerance is thought to be dependent, i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Seung, Edward, Cho, Josalyn L., Sparwasser, Tim, Medoff, Benjamin D., Luster, Andrew D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859457/
https://ncbi.nlm.nih.gov/pubmed/21555535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001049
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