BLT1-mediated T cell trafficking is critical for rejection and obliterative bronchiolitis after lung transplantation

Leukotriene B(4) is a lipid mediator that recently has been shown to have potent chemotactic activity for effector T lymphocytes mediated through its receptor, BLT1. Here, we developed a novel murine model of acute lung rejection to demonstrate that BLT1 controls effector CD8(+) T cell trafficking i...

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Main Authors: Medoff, Benjamin D., Seung, Edward, Wain, John C., Means, Terry K., Campanella, Gabriele S.V., Islam, Sabina A., Thomas, Seddon Y., Ginns, Leo C., Grabie, Nir, Lichtman, Andrew H., Tager, Andrew M., Luster, Andrew D.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212891/
https://ncbi.nlm.nih.gov/pubmed/15998790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042481
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