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Penalized Regression and Risk Prediction in Genome-Wide Association Studies

An important task in personalized medicine is to predict disease risk based on a person’s genome, e.g. on a large number of single-nucleotide polymorphisms (SNPs). Genome-wide association studies (GWAS) make SNP and phenotype data available to researchers. A critical question for researchers is how...

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Detalhes bibliográficos
Main Authors: Austin, Erin, Pan, Wei, Shen, Xiaotong
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859439/
https://ncbi.nlm.nih.gov/pubmed/24348893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sam.11183
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