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Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype–targeted drugs

Serotonin (5-hydroxytryptamine, or 5-HT) receptors mediate a plethora of physiological phenomena in the brain and the periphery. Additionally, serotonergic dysfunction has been implicated in nearly every neuropsychiatric disorder. The effects of serotonin are mediated by fourteen GPCRs. Both the the...

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Detalhes bibliográficos
Main Authors: Meltzer, Herbert Y., Roth, Bryan L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859385/
https://ncbi.nlm.nih.gov/pubmed/24292660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70678
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