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Theoretical and Practical Application of Traditional and Accelerated Titration Phase I Clinical Trial Designs: The Wayne State University Experience

The traditional and accelerated titration (AT) designs are two frequently utilized Phase I clinical trial designs. Although each design has theoretical advantages and disadvantages, a summary of the practical application of these theories has not been reported. We report our center's experience...

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Detalhes bibliográficos
Main Authors: Heath, Elisabeth I., LoRusso, Patricia M., Ivy, S. Percy, Rubinstein, Larry, Christian, Michaele C., Heilbrun, Lance K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859298/
https://ncbi.nlm.nih.gov/pubmed/19384685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543400902800460
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