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Crossing the Rubicon: New Roads Lead to Host Defense
Rubicon is a protein known to engage the Beclin-1/Vps34-PI3K/UVRAG complex and inhibit endosome and autophagosomal fusion with lysosomes. Yang et al. (2012) uncover new roles for this adaptor protein within noncanonical p22(phox) or CARD9 complexes that regulate oxidative and cytokine responses in a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3859237/ https://ncbi.nlm.nih.gov/pubmed/22423961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.02.005 |
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