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Beneficial effects of bumetanide in a CaV1.1-R528H mouse model of hypokalaemic periodic paralysis

Transient attacks of weakness in hypokalaemic periodic paralysis are caused by reduced fibre excitability from paradoxical depolarization of the resting potential in low potassium. Mutations of calcium channel and sodium channel genes have been identified as the underlying molecular defects that cau...

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Autori principali: Wu, Fenfen, Mi, Wentao, Cannon, Stephen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859222/
https://ncbi.nlm.nih.gov/pubmed/24142145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt280
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