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On the underlying assumptions of threshold Boolean networks as a model for genetic regulatory network behavior

Boolean networks (BoN) are relatively simple and interpretable models of gene regulatory networks. Specifying these models with fewer parameters while retaining their ability to describe complex regulatory relationships is an ongoing methodological challenge. Additionally, extending these models to...

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Autori principali: Tran, Van, McCall, Matthew N., McMurray, Helene R., Almudevar, Anthony
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859184/
https://ncbi.nlm.nih.gov/pubmed/24376454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00263
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