Interferon regulatory factor-8 modulates the development of tumour-induced CD11b(+)Gr-1(+) myeloid cells

Tumour-induced myeloid-derived suppressor cells (MDSC) promote immune suppression and mediate tumour progression. However, the molecular basis for the generation of MDSC, which in mice co-express the CD11b(+) and Gr-1(+) cell surface markers remains unclear. Because CD11b(+)Gr-1(+) cells expand duri...

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Detalhes bibliográficos
Main Authors: Stewart, Trina J, Greeneltch, Kristy M, Reid, Julia E, Liewehr, David J, Steinberg, Seth M, Liu, Kebin, Abrams, Scott I
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2009
Assuntos:
Molecular Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858838/
https://ncbi.nlm.nih.gov/pubmed/20196788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00685.x
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