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Modulating the Expression of Interferon Regulatory Factor-8 Alters the Pro-tumorigenic Behavior of CD11b(+)Gr-1(+) Myeloid Cells
CD11b(+)Gr-1(+)-expressing cells, termed myeloid-derived suppressor cells (MDSC), can mediate immunosuppression and tumor progression. However, the intrinsic molecular events that drive their pro-tumorigenic behavior remain to be elucidated. Although CD11b(+)Gr-1(+) cells exist at low frequencies in...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2744444/ https://ncbi.nlm.nih.gov/pubmed/19542426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804132 |
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