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Modulating the Expression of Interferon Regulatory Factor-8 Alters the Pro-tumorigenic Behavior of CD11b(+)Gr-1(+) Myeloid Cells

CD11b(+)Gr-1(+)-expressing cells, termed myeloid-derived suppressor cells (MDSC), can mediate immunosuppression and tumor progression. However, the intrinsic molecular events that drive their pro-tumorigenic behavior remain to be elucidated. Although CD11b(+)Gr-1(+) cells exist at low frequencies in...

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Autors principals: Stewart, Trina J., Liewehr, David J., Steinberg, Seth M., Greeneltch, Kristy M., Abrams, Scott I.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744444/
https://ncbi.nlm.nih.gov/pubmed/19542426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804132
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