Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila

The Unfolded Protein Response (UPR) is composed by homeostatic signaling pathways that are activated by excessive protein misfolding in the endoplasmic reticulum (ER). Ire1 signaling is an important mediator of the UPR, leading to the activation of the transcription factor Xbp1. Here, we show that D...

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Bibliografske podrobnosti
Main Authors: Coelho, Dina S., Cairrão, Fatima, Zeng, Xiaomei, Pires, Elisabete, Coelho, Ana V., Ron, David, Ryoo, Hyung Don, Domingos, Pedro M.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858604/
https://ncbi.nlm.nih.gov/pubmed/24183663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.09.046
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