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A modified UPR stress sensing system reveals a novel tissue distribution of IRE1/XBP1 activity during normal Drosophila development

Eukaryotic cells respond to stress caused by the accumulation of unfolded/misfolded proteins in the endoplasmic reticulum by activating the intracellular signaling pathways referred to as the unfolded protein response (UPR). In metazoans, UPR consists of three parallel branches, each characterized b...

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Detalhes bibliográficos
Main Authors: Sone, Michio, Zeng, Xiaomei, Larese, Joseph, Ryoo, Hyung Don
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631089/
https://ncbi.nlm.nih.gov/pubmed/23160805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-012-0383-x
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