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A modified UPR stress sensing system reveals a novel tissue distribution of IRE1/XBP1 activity during normal Drosophila development

Eukaryotic cells respond to stress caused by the accumulation of unfolded/misfolded proteins in the endoplasmic reticulum by activating the intracellular signaling pathways referred to as the unfolded protein response (UPR). In metazoans, UPR consists of three parallel branches, each characterized b...

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Autors principals: Sone, Michio, Zeng, Xiaomei, Larese, Joseph, Ryoo, Hyung Don
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631089/
https://ncbi.nlm.nih.gov/pubmed/23160805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-012-0383-x
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