Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine

The embryonic T-box transcription factor brachyury is aberrantly expressed in a range of human tumors. Previous studies have demonstrated that brachyury is a driver of the epithelial-mesenchymal transition (EMT), a process associated with cancer progression. Brachyury expression in human tumor cells...

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Hauptverfasser: Hamilton, Duane H., Litzinger, Mary T., Jales, Alessandra, Huang, Bruce, Fernando, Romaine I., Hodge, James W., Ardiani, Andressa, Apelian, David, Schlom, Jeffrey, Palena, Claudia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2013
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858563/
https://ncbi.nlm.nih.gov/pubmed/24125763
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