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BANK1 Controls CpG-induced IL-6 Secretion Via a p38 and MNK1/2- eIF4E Translation Initiation Pathway()
BANK1, an adaptor protein expressed in B-cells, plays a little understood role in B-cell signaling. Because BANK1 contains an N-terminal putative Toll-interleukin 1 receptor (TIR) domain, we used mouse Bank1(−/−) splenic B cells to test if BANK1 affects signaling induced by the TLR9 agonist CpG. Fol...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3858538/ https://ncbi.nlm.nih.gov/pubmed/24227780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301203 |
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