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Oncolytic vesicular stomatitis virus and bortezomib are antagonistic against myeloma cells in vitro but have additive anti-myeloma activity in vivo

Multiple myeloma cells are highly sensitive to the oncolytic effects of vesicular stomatitis virus (VSV), which specifically targets and kills cancer cells. Myeloma cells are also exquisitely sensitive to the cytotoxic effects of the clinically-approved proteasome inhibitor bortezomib. Therefore, we...

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Библиографические подробности
Главные авторы: Yarde, Danielle N., Nace, Rebecca A., Russell, Stephen J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858457/
https://ncbi.nlm.nih.gov/pubmed/24067362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.09.005
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