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Loss of hepatic aryl hydrocarbon receptor protein in adrenalectomized rats does not involve altered levels of the receptor’s cytoplasmic chaperones

The aryl hydrocarbon receptor (AHR) plays physiological roles and mediates adaptive and toxic responses to environmental pollutants. Adrenalectomized rats display decreased hepatic AHR protein levels, with no change in mRNA, and selectively impaired induction of cytochrome P450 1B1. This was similar...

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Hlavní autoři: Lee, Chunja, Mullen Grey, Anne K., Riddick, David S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858301/
https://ncbi.nlm.nih.gov/pubmed/24289088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/cjpp-2013-0238
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